Character experience
Born in Shengxian County, Zhejiang Province (now Shengzhou) in September 1957, native of Lin 'an, Zhejiang Province. He is a reproductive physician, academician of China Academy of Sciences, academician of the Academy of Sciences of Developing Countries, professor and doctoral supervisor of Shanghai Jiao Tong University, and medicine of Shanghai Jiao Tong University
Dean of the International Peace Maternal andChild Health Hospital Affiliated to the hospital, Director of the Key Laboratory of Reproductive Genetics of the Ministry of Education (Zhejiang University), Chief Physician of the Obstetrics and Gynecology Hospital Affiliated to Fudan University, Dean and Professor of the Institute of Reproduction and Development of Fudan University.
In September 1957, he was born in Ganlin Town, Shengxian County, Zhejiang Province (now Shengzhou), native of Lin 'an, Zhejiang. He successively studied in Changshan Kindergarten, Changshan No. 3 Primary School, Changshan No. 1 Middle School, and joined the queue in Xucun, Hudong Commune
In December 1982, Huang Hefeng graduated from the Department of Medicine of Zhejiang Medical University.
In 1989, Huang Hefeng graduated from Zhejiang Medical University majoring in Obstetrics and Gynecology with a master's degree in medicine.
In 1996, Huang Hefeng engaged in reproductive medicine research at the University of Cincinnati in the United States.
In 2001, Huang Hefeng successively served as vice president of scientific research and vice president of the Institute of Science and Technology of Zhejiang University School of Medicine.
In 2007, Huang Hefeng was hired as Qiushi Distinguished Professor of Zhejiang University
From July 2009 to July 2013, Huang Hefeng served as the dean of the Obstetrics and Gynecology Hospital Affiliated to Zhejiang University School of Medicine.
In July 2013, Huang Hefeng served as deputy director of the Department of Medicine of Zhejiang University. In the same year, he joined Shanghai Jiao Tong University and became the director of the International Peace Maternal and Child Health Hospital Affiliated to Shanghai Jiao Tong University School of Medicine.
In November 2017, Huang Hefeng was elected as an academician of China Academy of Sciences and was awarded the honorary academician of the Royal College of Obstetricians and Gynaecology in the same year
On February 9, 2018, the launching ceremony of Academician Huang Hefeng's Expert Workstation was held in the North Square of Changshan County People's Hospital. On March 23, Academician Huang Hefeng's Expert Workstation was officially launched in Shengzhou Maternal and Child Health Hospital. In November, Huang Hefeng was elected to develop China
Academician of the Academy of Sciences
In February 2024, he served as Dean of the School of Medicine of Zhejiang University.
nMajor achievements
nScientific achievements
nScientific Research Review
Huang Hefeng proposed the theory of "gametogenic diseases" for the first time internationally, and conducted groundbreaking research on the intergenerational and cross-generational genetic/epigenetic mechanisms of sperm/volunteer resource diseases. Short-term and long-term health of children born with assisted reproductive technology (ART)
The key scientific issues are the creation ofnew reproductive technologies through ART birth cohorts and basic research, improving the safety of IVF and blocking the source of genetic birth defects [10]. On May 18, 2022, the international high-end scientific and technological journal Natur
emagazine published an article online: "Maternal inheritance of glucose intolerance via oocyte Tet3 insufficiousness." This article publishes the latest major breakthrough in theintergenerational genetic research of diabetes by China scientists
Break sexand achieveresults. This research was completed by a team of Academician Huang Hefeng, Honorary Dean of the Obstetrics and Gynecology Hospital Affiliated to Zhejiang University School of Medicine, and Academician Xu Guoliang of the Chinese Academy of Sciences/Fudan University. Study confirms the origin of diabetes oocyte, revealing for the first time
showsthe precise regulation mechanism of epigenetic methylation in the intergenerational transmission of oocyte diabetes. The study also found that the female parent Tet3 (tet methylcytosine dioxygenase 3) regulates theparental genetic characteristics of the male parent, making the child
insulinsecretionis insufficient, which leads to the intergenerational inheritance of diabetes susceptibility, providing a new scientific perspective for understanding and preventing and controlling adult chronic diseases such as diabetes. [21]Academician Huang Hefeng's research group is the earliest source of development in the world
One of the teams working on sexual disease research has long been committed to studying the mechanism of adult diseases caused by maternal exposure to environmental factors during pregnancy. It has been confirmed for the first time that intrauterine high glucose exposure during pregnancy and other factors can change the intergenerational inheritance caused by DNA methylation
At the same time, it was discoveredthat theorigin of the disease could be advanced to pre-pregnancy (gamete development period), and it was the first to propose the theory of "gametogenic adult disease" internationally. However, compared to direct exposure to the fetus during pregnancy, how can gametes or germ cells cause the adverseenvironment
The hormone is transmitted to thelatergeneration, but the relevant mechanism of action has not yet been clarified. [22]
Academic Books
As of July 2018, Huang Hefeng has published more than 120 SCI papers in PNAS, Nat Med and other journals as a correspondent and co-correspondent author. Editor-in-chief of the domestic leading ART reference book "Modern Assisted Reproductive Technology", and the first book "Human ART Pro
Bed Diagnosis and Treatment Guidelines "[11].
2018.08 "Clinical Practice of Preimplantation Genetic Diagnosis" Huang Hefeng Shanghai Jiao Tong University Press
2018.08 Practical Human Assisted Reproductive Technology 2018 Edition Huang Hefeng Beijing: People's Medical Publishing House
2016.01 "Baby Come 27 Senior Doctors Analyze Infertility" Edited by Huang Hefeng, Zhejiang Science and Technology Press
2013.06 "Clinical Diagnosis and Treatment Routine of Reproductive Medicine" Huang Hefeng and other deputy editor-in-chief Beijing: People's Military Medical Press
2013
2009.09 Clinical Diagnosis and Treatment Guidelines Assisted Reproductive Technology and Sperm Bank Volume Compiled by Huang Hefeng Beijing: People's Medical Publishing House
2004.02 "Guidelines for Pregnancy with Assisted Reproductive Technology", edited by Huang Hefeng and others, Beijing: People's Military Medical Press
2003.0 "Modern Assisted Reproductive Technology" Editor of Huang Hefeng Beijing: People's Military Medical Press
2003.05 "High-risk Pregnancy" Editor of Huang Hefeng Beijing: People's Military Medical Press
2000.02 "Abortion" edited by Huang Hefeng and Han Xiujun Beijing: Rural Books Publishing House
2000.02 "Irregular Menstruation" Edited by Huang Hefeng and Chen Danqing Beijing: Rural Reading Press
Commitment Items
As of July 2018, Huang Hefeng has successively undertaken scientific and technological support for the "863","973","12th Five-Year Plan" and national key research and development plans [11].
2013.1.1-2017.12.31 Research on the Mechanism of the Transformation of Spermatogonia into Germ Stem Cells and Germ Cells, Project Leader of the National Major Scientific Research Program
2012.1.1-2016.12.31 Risk assessment and mechanism research on assisted reproduction induced embryo-derived diseases Chief Scientist of the National Major Scientific Research Program
2012.1.1-2016.12.31 Reproductive health status assessment and key technology research project leader of the National Science and Technology Support Plan
2011.1.1-2013.12.31 Research on the Regulation and Effect Mechanism of High Glucose on the Igf2/H19 Differential Methylation Region during the Differentiation of Human Embryonic Stem Cells into Islet Cells, National Natural Science Foundation of China Project Leader
2010.1.1-2012.12.31 Research on the Effect of High Intrauterine Glucose Environment during Pregnancy on Parental Gene Imprints and Its Genetic Effect Mechanism, National Natural Science Foundation of China Project Leader
2007.6.1-2010.11.30 Proactive Eugenics Path--Clinical Application and Promotion of Preimplantation Embryo Gene Diagnosis Technology, National High-Technology Research and Development Plan (863) Project Leader
2006.12.14-2009.12.31 Establishment and application of human (disease) embryonic stem cell bank in my country, project leader of the National High-tech Research and Development Plan
2006.6.1-2011.12.31 Network Regulation Mechanism for Maternal and Fetal Identification of Homogeneous and Interspecies Pregnancies, Project Leader of the National Major Scientific Research Program
2006-2009 Expression, function and role of Ca-activated K channel in human endometrial cells in embryo implantation, National Natural Science Foundation of China Project Leader
Research on the Regulation Mechanism of Ov-derived Growth Factors on Human Follicle Development, Project Leader of the China-Canada Health Research Cooperation Project of the National Natural Science Foundation of China
nScientific research achievement reward
As of 2021, Huang Hefeng has won the first prize of Zhejiang Province Scientific and Technological Progress Award and the second prize of National Scientific and Technological Progress Award as the first finisher [10].
Second prize in the 2021 National Science and Technology Progress Award for Mechanism Research and Clinical Precise Prevention and Control of Developmental Diseases and Hereditary Birth Defects [17] Huang Hefeng, Xu Chenming, Ding Guolian, Wu Yanting, Chen Songchang, Zhang Jinglan, Chen Xiaozhang, Zhao
Huan, Gao Ling, Chen Qian [18]
Second Prize in the 2011 National Science and Technology Progress Award for Research and Clinical Application of the Causes and Treatment of Infertility Qiao Jie, Huang Hefeng, Sun Yingpu, Yan Liying, Qu Fan, Liu Ping, Ma Caihong, Xu Jian, Li Rong, Huang Jin [19]
Second prize of the National Science and Technology Progress Award for the Creation, System Optimization and Clinical Promotion and Application of Reproductive Technology to Improve the Quality of Birth Population in 2010 Huang Hefeng, Chen Zijiang, Liu Jiayin, Lin Jun, Lu Shiming, Jin Fan, Zhu Yimin, Dong Minyue, Xu
Chenming, Weng Binghuan [20]
2011 First prize for the creation, system optimization and clinical promotion and application of reproductive technology to improve the quality of births in the national population/family planning "Eleventh Five-Year Plan"[12]
2010 First prize in the Zhejiang Province Science and Technology Award for the creation and promotion of key technology systems to block birth defects and promote the health of offspring
2007 Second Prize in the Zhejiang Province Science and Technology Award for Research on Endometriosis and Female Infertility
First Prize in the 2004 Zhejiang Province Science and Technology Award for Basic and Clinical Research on Assisted Reproductive Technology
2001 Embryo Cryopreservation, Resurrection and Transplantation, Second Prize in Zhejiang Province Science and Technology Award
1996 Assisted Reproductive Technology (Test Tube Baby, Gift Baby) Second Prize in Zhejiang Province Science and Technology Award
Talent training
Since Huang Hefeng became the president of the Obstetrics and Gynecology Hospital in 2009, she has advocated the close integration of clinical and basic research and focused on the training of full-time scientific researchers, making the hospital a scientific research base. Progress has been made in terms of talent training and discipline construction.
Huang Hefeng hascultivated an excellent scientific research team with distinctive characteristics since his career as medicine and teaching, and has made important efforts in the research on reproductive safety and optimization of the fertility assistance system.
Honor
In 2005, young and middle-aged experts with outstanding contributions in Zhejiang Province
2006 National Model for Female Employees in Making Contributions and Making Achievements [13]
Young and middle-aged experts with outstanding contributions from the Ministry of Health in 2010
2012 National March 8 Red Flag Bearer [14]
Academician of China Academy of Sciences in November 2017 [10]
2017 Fellow Honoris Causa
Academician of the Academy of Sciences of Developing Countries, November 2018 [3]
July 2023 Fuller W. Bazer SSR International Scientist Award [23]
Social appointment
Huang Hefeng serves as the chairman of the "Reproductive Medicine" Professional Committee of China Society of Integrated Traditional Chinese and Western Medicine, the chairman of the "Reproductive Health" Professional Committee of China Maternal and Child Health Association, and the vice president of China Maternal and Child Health Association, serving as
Editorial board member of 7 SCI magazines including Endocrinology and FertilSteril [15], visiting professor at the University of Adelaide, Australia, and member of the National Health Science Popularization Expert Database. [16]
On July 19, 2018, he was hired as a "double academician" of Nantong University [11].
Huang Hefeng graduated from Zhejiang Medical University in 1982
Received a master's degree in medicine from Zhejiang Medical University in 1989
Engaged in reproductive medicine research at the University of Cincinnati in 1996
Since 2001, he has served as vice president of scientific research and vice president of the Institute of Science and Technology of Zhejiang University School of Medicine
In 2007, he was hired as Qiushi Distinguished Professor of Zhejiang University
In 2009, he served as director of the Obstetrics and Gynecology Hospital Affiliated to Zhejiang University School of Medicine (term until 2013)
Joined Shanghai Jiao Tong University in 2013 and became the dean of the International Peace Maternal and Child Health Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Elected as an academician of China Academy of Sciences in 2017, and was awarded the honorary academician of the Royal College of Obstetricians and Gynaecology in the same year
Elected as an academician of the Academy of Sciences of Developing Countries in November 2018. Huang Hefeng is engaged in clinical and basic research in obstetrics and gynecology and reproductive medicine. His main research direction is reproductive medicine and reproductive genetics, with the research focus on the safety of human ART and ART inheritance
Epigenetic genetic effects.
