Lelaiwa Consulting Service Center
Yao Guangxin
Title: Research intern
Doctor Profile

Educational background

Graduated from the Institute of Biochemistry and Cell Biology, Shanghai Institute of Life Sciences, China Academy of Sciences, in 2016, with a doctorate of science. In July of the same year, he worked at Shanghai Communications University

The Reproductive Medicine Center of Renji Hospital Affiliated to the School of Medicine is mainly engaged in assisted reproduction in the embryo laboratory and scientific research related to reproductive medicine, and is committed to elaborating on reproductive history

Pathology-related physiological and pathological basis and molecular mechanism

nResearch results
nResearch direction Reproductive biology
nResearch content 1. Establishment of endometrial receptivity and molecular mechanisms of embryo implantation
2. Molecular mechanisms of spermatogenesis and maturation
Representative paper

1, Di F#, Liu J #, Li S#, Yao G, Hong Y, Chen ZJ, Li W, Du Y*: ATF4 promotes ovulation and regulates COX2/PGE2 Table

Da: The potential role of ATF4 in PCOS. Front Endocrinol (Lausanne) 2018, 9:669.


2, Hu S#*, Liang A#, Yao G#, Li X, Zou Ming, Liu Jie, Sun Y*, Dynamic metabolomic changes in the entire mouse epididymis fluid may contribute to sperm formation

cooked. Andrology Journal 2018, 6 (1): 247-255.


3, Yao G#, Hu S, Yu L, Ru Y, Chen CD, Liu Q*, Zhang Y*: Genome map in vivo ERalpha binding in efferent ducts of male mice

Bit. Endocrinology 2017, 158 (11): 3724-3737.


4, Xu J #, Yao G, Ru Y, Xie S*: Tamoxifene-induced expression of CRE recombinase in the epididymis of Lcn5-CreERT2 transgenic mice. Molecular's 2016

Reproduction and development.


5, Gao Hui #, Ma W#, Nie Jie #, Zhang C, Zhang J, Yao G, Han J, Xu Jie, Hu B, Du Y, Shi Q, Yang Z*, Huang X*, Zhang Y*: A G-Four-Chain

The somatic DNA structure analyzing enzyme RHAU affects the differentiation of spermatogonia. Cell Death and Disease 2015, 6: E1610.


6, Hu S#, Zou Ming, Yao G, Ma W, Zhu Q, Li X, Chen Z, Sun Y*: Androgens regulate beta-defensin in the epididymis of mice. Reproductive Biology and Endocrinology

Science: RB& E 2014, 12:76.


7, Hu S#, Yao G, Wang Y, Xu H, Ji X, He Y, Zhu Q, Chen Z, Sun Y*: Transcriptomics: Human transition from pre-acceptance to acceptance

Changes were detected by RNA-Seq in the endometrium. Clinical Journal of Endocrinology and Metabolism 2014, 99 (12): E2744-2753.


8, Ma W#, Hu S, Yao G, Xie S, Ni Ming, Liu Q, Gao X, Zhang J, Huang X*, Zhang Y*: Regulation of androgen receptor-microRNA-29a in An mice

Circuit epididymis. Journal of Biochemistry 2013, 288 (41): 29369-29381.


9, Hu S#, Yao G, Li X, Chen Z, Sun Y*: Androgen receptor binding site identified in mouse testis. Journal of Biochemistry and Biophysics, 2013

45(9):795-797.


10, Xie S#, Xu J #, Ma W, Liu Q, Han J, Yao G, Huang X*, Zhang Y*: The Lcn5 promoter directs the expression of region-specific CRE recombinase in the transgenic epididymis

Mouse. Reproductive Biology 2013, 88 (3): 71.


11, Wang C#, Hu S#, Ru Y#, Yao G, Ma W, Gu Y, Chu C, Wang S, Zhou Z, Liu Q, Zhou Y, Zhang Y: Androgen affects Fut1, Fut2

Different effects of Fut4 expression and Fut9 in the reproductive tract of male mice. International Journal of Molecular Science 2013, 14 (11): 23188-23202.


12, Hu S#, Du H#, Yao G, Zhang Y*: Molecular cloning and identification of the epididymi-specific gene mHong1 in mice, a homologue of rat HongrES1. Ya

European Journal of Andrology 2012, 14 (4): 626-634.


13, Hu S#, Yao G, Guan X, Ni Zhi, Ma W, Wilson EM, France FS, Liu Q*, Zhang Y*: Research Resources: The entire genome of androgen receptors in vivo

Mapping binding sites in mouse epididymis. Molecular Endocrinology 2010, 24 (12): 2392-2405.


14. Hu Shuanggang, Yao Guangxin, Sun Yun. Study on the regulation mechanism of androgen/androgen receptor on Caveolin-1 expression in mouse epididymis. Chinese Journal of Male Science 2013, 19

(10) : 867-872


15, Hu Shuanggang, Yao Guangxin, Zhao Xiaoming, Sun Yun, Gao Yuping. Construction of eukaryotic expression vector of human HoxA10 gene and identification of expression products. Reproduction and Contraception 2013, 33

(6):383-386


16. Yao Guangxin, Zhang Yixuan, Hu Shuanggang. Protein-mediated prokaryotic soluble expression, purification and activity identification of recombinant human AR DBD. China Journal of Bioengineering 2011

30(4):7-11


17. Zhang Leilei, You Pengfei, Yao Guangxin, Marquis, Zhang Yixuan. Establishment of a screening model for new anti-mycobacterium tuberculosis drugs. Journal of Microbiology 2011, 31 (1): 57-

62


online consultation
ONLINE CONSULTATION
LINE QR code
Email an advisor
Yao Guangxin