She hadn't given up yet. In order to have a second child, she traveled to the other side of the ocean and tried every possible method. But in the end, all three eggs were empty. Just when she was about to give up, a rational choice changed everything.
1. The starting point of the story: A difficult situation with limited ovarian reserve
The protagonist was 34 years old and already had one child through natural reproduction. When the plan for having a second child was discussed, her age and test results gave her a huge setback-her AMH level was only 0.22–0.8 ng/mL, indicating a significant decline in ovarian reserve.
In short, low AMH levels mean there are fewer available follicles in the ovaries, which is considered a major challenge in assisted reproductive technology. Her regular menstrual cycle (26–28 days) and absence of any medical or family history were some of the good news.
2. The first step: A trip to the US, filled with disappointment due to empty eggs
With hopes that foreign technologies would be more effective, she decided to undergo IVF treatment in the US. Initial tests showed that she had 12 follicles. The doctor recommended a intensive treatment plan:
The treatment plan in the US included:
High-dose gonadotropins (Gonal-F): 300–375 IU/day, for more than 10 days
High-dose oral contraceptives (Clomid + Tamoxifen): 100mg/day + 40mg/day, for the first 5 days
Although the treatment plan seemed effective, the result was heartbreaking-only 3 eggs were retrieved, and all of them were empty. High-dose stimulation...
It didn't lead to the expected maturation of the follicles. Instead, it resulted in nothing but wasted effort, and her hopes were instantly dashed.III. Starting Over: Choice Is Often More Important Than Effort
One failure doesn't mean there's no way out. What matters more is the right direction to take. After returning to her country, she was lost for a while until she finally recognized her true situation: her AFC score wasn't bad, but the main problem was the low rate of egg maturation.
At LeLaiWa International Fertility Center, her test results were carefully evaluated. The professional team determined that she wasn't suffering from absolute ovarian failure. What was more important was finding ways to increase the percentage of mature eggs. Based on this, LeLaiWa International Fertility Center matched her with theThai DanRuo Reproductive CenterIV. The Second Round: Thailand's Comeback
This time, the treatment approach shifted from aggressive methods to more precise techniques. The entire process was carried out with the help of LeLaiWa International Fertility Center's remote coordination and arrangements for traveling to Thailand.
① Pre-treatment Phase (Before traveling to Thailand, approximately February 16th)
Based on the patient's hormone levels and ovarian response, it was determined that no down-regulation drugs or pre-treatment was necessary. Although her AMH level was low, she wasn't in a state of absolute ovarian failure, so gentle stimulation was appropriate.
② Stimulation Phase (February 16th–25th)
Gradual progression:
trong>The initial dose of the medication used to promote ovulation is quite low.150 IUAfter that, the dosage will be adjusted gradually based on the patient's response, to avoid excessive stimulation.simultaneous controlLHPeak valueOral administration of dydrogesterone can be effective for a prolonged period of time.Reduce the risk of premature ovulation due to follicular precocity.
Join in the middle and later stages.GnRHAntagonist:This can ensure a successful egg retrieval process.The time point is in its optimal state.
It's worth mentioning that Leila International Fertility provides sophisticated remote coordination services at this stage. Patients can receive injections at home, and they can regularly receive updates on their test results. Professional medical teams also help to plan the timing of egg retrieval procedures, as well as the journey to Thailand. This ensures that the entire process is more comfortable, Organized and controllable.
③ Egg retrieval and laboratory culture) February 25th: Egg retrieval should be performed on days with sunlight.
Proportion of mature eggs:0% →rgb(51, 51, 51); font-family: Microsoft YaHei;">0% → 80%(Per unit)5At least one of the retrieved eggs is viable.4 mature eggs)
It will eventually be obtained.3One blastocyst, among them1One for4AAHigh-quality embryos at a high level.
From an empty egg to a 4AAHigh-quality embryos not only represent a numerical improvement, but they also symbolize the hope of entire families.

All of them3All of the embryos passed the screening process.
**V. Expert Analysis: What Made This Success Possible?**
Why did the results differ so much in these two cases? Looking at this case, we can identify three key factors:
① Choosing the right approach is more important than increasing the dosage.
Women with low AMH levels have more sensitive and fragile ovaries. High-dose stimulation may have the opposite effect. Gentle ovulation induction, gradual dose escalation, combined with continuous LH suppression and precise control using antagonists, can significantly increase the proportion of mature eggs.
② Choosing the right platform is more important than simply going abroad.
Laboratory techniques and the ability to adjust the treatment plan dynamically directly affect the quality of embryos.Danor Reproductive Center in ThailandHas extensive experience in treating patients with low ovarian reserve. This is why Le Laiwa International Fertilization Partners chose this center for their services.
③ Warmth and care are essential for building confidence.
The biggest fear when seeking medical care abroad is being alone. Professional remote coordination and full-process support can greatly alleviate patients' psychological stress, giving them more confidence throughout the process.
**VI. Lessons Learned: Choosing the Right Platform Is Crucial for Fertility Protection.**
What's most touching about this case is that even if the AMH level is low or if there have been previous failures abroad, as long as the direction, platform, and methods are correct, the outcome can still be changed for the better.
.It also serves as a reminder to every woman who is working hard along this path-failure is not scary. What's truly terrifying is wasting time on the wrong path over and over again. A professional medical team, top-notch laboratory technology, and a warm service system-these three combined are what truly support you on your journey towards successful pregnancy.
The hardest part of preparing for pregnancy isn't taking injections or taking medication. It's feeling unsure whether what you're doing is right. Leilawa International Pregnancy Assistance doesn't make blind recommendations or create anxiety. We carefully evaluate your test results and match you with suitable hospitals and doctors, allowing our professional judgment to ensure your success.
This is a real case study. The treatment plan is tailored by reproductive doctors. Individual results may vary. Please rely on the evaluations provided by doctors.