1. Normal recovery time:About 14 days is the mainstream, fluctuations are normal

Physiological mechanism

The oocyte retrieval operation time point is equivalent to the ovulation period of the natural cycle, and withdrawal bleeding (i.e. menstruation) caused by atrophy of the corpus luteum after ovulation is usuallyabout 14 days apart. Therefore, most womenhave their first menstruation 10 to 15 days after egg retrieval.

Special circumstances: If embryo transfer is not performed and corpus luteal support drugs are not used, some people may have arrived9 to 12days earlier.

The individualized fluctuation range

Within 7 days of advance or delay is the normal range, which is related to differences in ovarian recovery speed and metabolism of excretion-promoting drugs.

Case evidence: Clinical statistics show that about70% of patients resume menstruation 14±2 days after surgery.

2. Four key factors affecting menstrual recovery

Number of oocytes retrieved and ovarian stimulation

When the number of oocytes retrieved in a single time is greater than15, the risk of ovarian overstimulation is increased, which may lead to delayed menstruation for 3 to 7 days (additional recovery time is required).

Effect of drug residues

Effluent promoting drugs (such asHCG) interfere with the hypothalamic-pituitary-ovarian axis, especially long-acting preparations may prolong the endocrine regulation cycle.

Physical and emotional state Staying up late after surgery and excessive stress will inhibit hormone secretion and delay menstruation Excessive dieting or strenuous exercise (such as skipping, running) disrupts energy balance and affects the rhythm of endometrial shedding.

Potential pathological factors Lluteal dysfunction: Insufficient progesterone secretion requires exogenous luteal support Potential pathological factors

Accompanied by dangerous conditions

Nutritional fortification plan

Protein:≥60g per day (2 eggs +150g fish), repair ovarian tissue Nutrition fortification plan

List of behavioral taboos

·Prohibited within 2 weeks: sharing rooms, taking baths, lifting heavy objects>3kg

·Avoid raw, cold and spicy (easy to cause pelvic congestion).

tMonitoring and recording

·Basic body temperature method: Continuously monitor morning temperature, and a sudden drop of0.3℃ to 0.5℃ indicates that the rush within 24 hours

·Abnormal tracking: Record the amount of bleeding (daily sanitary napkins>5 pieces/day is excessive).

Treat fluctuations rationally and scientifically avoid risks

The director of the Reproductive Center of Peking Union Medical College Hospital:"No intervention is needed for menstrual delays ≤7 days after egg retrieval, but three major problems must be investigated for more than 45 days: possible pregnancy, ovarian failure, and intrauterine adhesions. Especially for women over 35 years old, it is recommended to review AMH and estrogen levels 30 days after surgery to dynamically assess ovarian reserve."