Q1: What is the official definition of embryo glue?
(Embryo Glue)“”,,().By simulating the internal environment of a woman's uterus, it helps embryos adhere more stably to the endometrium after transplantation and reduces the risk of detachment, so it is vividly called "glue".
nCore ingredients:
·Hyaluronic acid: It occurs naturally in the uterus and ovaries. It can increase the viscosity of culture medium and simulate the characteristics of uterine fluid.
· Hyaluronic acid: Naturally found in the uterus and ovaries, this substance can increase the viscosity of the culture medium, thereby simulating the properties of uterine fluid.
· Recombinant human albumin: replaces traditional blood-derived components, reducing the risk of allergies.
· Amino acids and sugars: provide nutritional support for the embryo.
·Physical adhesion: The thickened culture medium brings closer contact between the embryo and the endometrium, reducing the expulsion of embryos caused by uterine contraction.
· Physical adhesion: The thickened culture medium allows for closer contact between the embryo and the uterine lining, thereby reducing the risk of embryo expulsion due to uterine contractions.
·:CD44,.Environmental optimization: Adjust the pH value and nutrient concentration of the uterine cavity to improve the survival rate of embryos.
Q3: Who needs to use embryo glue?
·:.
·Women in their late 30s (≥35 years old): The receptivity of the endometrium decreases, thus it is necessary to enhance the ability to locate embryos.
·Thin endometrium or insufficient blood flow: Compensation for endometrial function is achieved through adhesion mechanisms.
·High-quality blastocyst transfer: Even if the quality of the embryo is high, the risk of ectopic pregnancy can still be reduced through the use of embryo gel.
·Uterine malformation or severe adhesions (surgical correction is required first).
·Those with uterine malformations or severe adhesions (require surgical correction beforehand).
·Allergic to hyaluronic acid (rare case).
Operation steps:
·1 hour before transfer: Mix the embryos with embryo gel and thicken the medium.
·1 hour before transplantation: Mix the embryo with the embryo culture medium to make the medium thicker.
·During transplantation, the embryo-colloid mixture is injected into the uterine cavity using a catheter.
·Postoperative observation: No special treatment required. Pregnancy can be confirmed after 1-2 weeks.
·Fees: The increase in a single cycle is about 3,000 - 5,000 yuan, and some hospitals include packages.
·Costs: Approximately 3,000 to 5,000 yuan increase per cycle. Some hospitals offer packages that include these costs.
·Psychological expectations: There is no guarantee of success. It is necessary to consider the quality of the embryo and the state of the endometrium in order to make an informed decision.
·Side effects: No adverse effects on embryos or the mother have been observed in current studies. Occasionally, there may be a slight feeling of abdominal distension.
Q5: Do clinical data support the effectiveness of embryonic gel?
·Repeated failures increased by 18%.
·Those who repeatedly fail see their performance improve by 18%.
·Reduction in abortion rates: The abortion rate among patients with polycystic ovary syndrome (PCOS) has decreased by approximately 12%.
·Prevention of ectopic pregnancy: The incidence has been reduced from 2%-3% to 0.5%-1%.
·European Society of Human Reproduction and Embryology (ESHRE): Recommended for elderly and repeated failures.
·European Society of Human Reproduction and Embryology (ESHRE) recommends using this method for older individuals and those who have experienced multiple failed attempts.
·Some hospitals in China have begun incorporating embryo gel into their standard transplantation procedures.
Embryo glue provides a dual "physical + biological" guarantee for embryo implantation and is especially suitable for specific groups of people.
“+”,.However, it should be noted that the effect varies from person to person, and it is recommended to choose after evaluation by a doctor. If you plan to use it, you can consult the hospital in advance whether it provides the service and understand the medical insurance coverage.