① Fallopian tube infertility
Bilateral fallopian tube blockage, hydronephrosis, or resection (such as tuberculous lesions) will completely block sperm-egg integration.

Clinically confirmed that the probability of natural pregnancy in such patients is extremely low. IVF technology can bypass fallopian tube obstacles and transfer embryos directly into the uterine cavity. The first successful case of IVF in Jingdezhen originated from the patient's bilateral fallopian tubes blocked and underwent embryo transfer. Successful pregnancy.
② Male severe fertility disordersFor oligospermia (sperm concentration <15 million/ml), obstructive azoospermia, etc., high-quality sperm can be screened to complete fertilization through testicular puncture and in vitro fertilization.
research shows
③ Advanced age and decline of ovarian functionThe fertility of women after the age of 35 is only 25% of that of 25 years old. Patients with premature ovarian failure (AMH <1.1ng/ml) or women over the age of 38 should be given priority if drug treatment is ineffective.
Data from 2025 shows that for example, 38-year-old Ms. Zhang from Baoding successfully gave birth through a test tube after being diagnosed with premature ovarian failure.
④ Endometriosis and repeated abortionModerate to severe endometriosis can easily cause pelvic adhesions and ovarian cysts, leading to failed implantation of the fertilized egg.
If a patient has experienced more than 3 failed artificial insemination or repeated miscarriages, in vitro fertilization technology can avoid the impact of pelvic lesions and reduce the risk of abortion through embryonic genetic screening (PGT).
④ Unexplained infertility and immune factorsPatients with immune infertility (such as anti-sperm antibodies) also need to be intervened as soon as possible after three failed artificial insemination attempts, and those who have not been pregnant after more than 1 year of standardized preparation and no clear cause of pregnancy are excluded.

In 2025, 31 provinces across the country and the Xinjiang Production and Construction Corps will incorporate assisted reproductive technology into medical insurance. The core changes include
Reimbursement coverage: Core items such as oocyte retrieval, embryo culture, and transplantation are included in medical insurance, 60%-70% of employee medical insurance is reimbursed (such as Beijing and Shandong), and 50% of resident medical insurance is reimbursedGeographical expansion: Jiangxi, Shanghai and other 12 provinces and cities will add 12 new reimbursement items starting from June 2025, and Shandong patients 'single-cycle expenses can be reduced by 13,000 yuan
Elderly support: Some provinces have opened up higher reimbursement rates for people over the age of 38 to reduce economic pressure.

Three-generation test tube technology (PGT): Couples over the age of 45 can use pre-implantation genetic testing to screen embryos with chromosomal abnormalities. A couple who lost their children in Guangzhou successfully gave birth to a healthy male boy using this technology
Hormone-free excretion technology: New CAPA-IVM solutions (such as HerCAPATM) do not require hormone injection and retrieve oocytes directly from small follicles in the natural cycle, reducing the risk of ovarian overstimulation, and are especially suitable for patients with polycystic ovary syndrome.


ConclusionThe passage of fertility is irreversible, especially when the fallopian tubes are permanently damaged, sperm quality is extremely low, ovarian function declines, or repeated pregnancy assistance fails. Waiting may mean a permanent loss of opportunity.
With the comprehensive coverage of medical insurance policies and technological advancement, IVF has become the "core option" for scientifically assisted pregnancy. It is recommended that patients who meet the indications go to the Reproductive Medicine Center for evaluation as soon as possible so that technology can press the "acceleration button" for life.