Thalassemia gene is missing. Is test-tube baby the light of hope?

Thalassemia, referred to as thalassemia, is a common inherited blood disease. Among them, sea deletions and 3.7 deletions are the more common types. For couples with these gene deletions, birth

Having a healthy baby has become a major concern. So, can they realize this wish through IVF technology? The answer is yes, but it needs to be considered based on a combination of various factors.

First of all, preimplantation genetic diagnosis (PGD) and preimplantation genetic screening (PGS) in IVF technology have brought hope to thalassemia patients. Through these techniques, it is possible to detect the effects of the embryo

Genetic testing was carried out on the embryos before transfer to screen out healthy embryos that did not carry the thalassemia gene for transfer.

However, this process is not simple and straightforward. The situation of thalassemia sea deletion and 3.7 deletion is complex and requires professional genetic counseling and detailed genetic testing to assess the specific situation of both couples.

For example, if both couples are carriers of the homothalassemia gene, obtaining healthy embryos through IVF may be relatively difficult, but not completely impossible.

In actual operation, IVF technology requires a series of steps, including ovulation promotion, egg retrieval, fertilization, embryo culture and genetic testing. Every link requires careful operation and strict control of

Control

It is necessary to clarify the type and specific circumstances of thalassemia gene carrier in both couples. If only one party carries it, the risk is relatively small; if both parties carry it, especially the homotypic thalassemia gene, the situation is

It will be more complicated.

PGD (Preimplantation Genetic Diagnosis) and PGS (Preimplantation Genetic Screening) are the key in IVF technology. Through these technologies, embryos can be genetically tested and

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Embryos without thalassemia gene were transplanted.

For example, there is a couple. The man carries the thalassemia sea deletion gene and the woman carries the 3.7 deletion gene. After detailed genetic analysis and genetic testing during the IVF process, Jian

Kang's embryo was transplanted and finally welcomed a healthy baby.

Therefore, before deciding whether to perform IVF, you must fully communicate with a professional doctor, weigh the pros and cons, and make psychological and financial preparations.